Safest Cities In Southern California 2024. After the top three of danville, rancho santa margarita, and moorpark, the safest cities in california are lincoln, aliso viejo, rancho palos verdes, san ramon, mission viejo,. A new report by safewise has named multiple cities in southern california the safest spots to live in the state.

We all want a safe place to call home. In orange county, rancho santa margarita ranked as the safest city in the state.